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Inhibition of histone acetyltransferase attenuates 3D chromatin-mediated insulin signaling in pancreatic cancer (Hi-C dataset)

ABSTRACT: Inhibition of histone acetyltransferase has been widely used to be effectively treat cancers in many studies. However, it’s not clear how the downstream signaling responds to the inhibitor in pancreatic cancer. Here we performed Hi-C experiments to canonical and patient-derived pancreatic cancer cells with the treatment of small molecule inhibitor ICG-001 which has dual function to block both WNT signaling and histone acetyltransferase. This is in situ Hi-C dataset.

ORGANISM(S): Homo sapiens

PROVIDER: GSE197293 | GEO | 2024/06/10

REPOSITORIES: GEO

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