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RNase A treatment increases the recruitment of p65 to DNA

ABSTRACT: We investigated the ability of the NFkB protein p65 to bind DNA after RNA digestion. In this ChIP-seq experiment, we investigated the genome-wide binding profiles of p65 in Jurkat cells. We demonstrated that p65 binding to promoters and promoter proximal regions is enhanced by digestion of RNA with RNase A.

ORGANISM(S): Homo sapiens

PROVIDER: GSE197704 | GEO | 2022/03/08

REPOSITORIES: GEO

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