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Effect of deletion of Irf3, Irf7 or Irf9 on gene expression in sgScd2 Th1 cells.

ABSTRACT: To investigate the role of the IRF family in the regulation of interferon stimulated genes, we conducted CRISPR/Cas9 mediated genome editing of Irf3, Irf7 or Irf9 in sgScd2 Th1 cells. We then performed gene expression profiling analysis using data obtained from RNA-seq of control, sgScd2, sgScd2/sgIrf3, sgScd2/sgIrf7 or sgScd2/sgIrf9 Th1 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE200636 | GEO | 2022/08/03

REPOSITORIES: GEO

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