Transcriptomics

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Doxorubicin response in a triple negative breast cancer cell model: long-term resistance versus short-term stress


ABSTRACT: We have used a cell model for triple negative breast cancer, CAL51 cells, to study the transcriptional profiling of chemotherapy drug response. A doxorubicin resistant derivative has been generated, named CALDOX, which is able to proliferate in the continuos presence of 0.4 micro molar doxorubicin in the culture medium. In addition, both naive CAL51 and drug resistant CALDOX cells, the short-term response to doxorubicin treatment has been studied.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202536 | GEO | 2023/02/27

REPOSITORIES: GEO

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