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In vitro biocompatibility of ZrO2 vs Y-TZP alloys on Saos-2 cells: influence of composition and surface topography

ABSTRACT: This study assess the biocompatibility of ZrO2 vs Y-TZP alloys on Saos-2 cells, through the combination of conventional toxicological assay, morphological observations and transcriptomic analysis performed on Saos-2 cells. The biocompatibility of ZrO2 alloys was evaluated in comparison with Y-TZP alloys, studying cell proliferation (WST-1) and cell morphology/adhesion (SEM) on human Saos-2 cell lines. Finally, an evaluation of gene expression was performed on Y-TZP alloys rough surface that seems more interesting regarding biocompatibility results.

ORGANISM(S): Homo sapiens

PROVIDER: GSE203572 | GEO | 2022/07/13

REPOSITORIES: GEO

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