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Effect of mesenchymal stem cells on gene expression of fibroblasts when they were co-cultured

ABSTRACT: Our research and previous reports showed that fibroblasts could inhibit osteoblast differentiation of Mesenchymal stem cells (MSCs). Thus, RNA-seq was carried to analyze the transcriptome differences among fibroblasts cultured alone and fibroblasts co-cultured with MSCs to find detailed mechanisms about how fibroblasts had functions on MSCs. We then performed gene expression profiling analysis using data obtained from RNA-seq of fibroblasts cultured alone or co-cultured with MSCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE205156 | GEO | 2022/06/03

REPOSITORIES: GEO

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