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Tensile strain and altered synovial tissue metabolism in human knee osteoarthritis

ABSTRACT: To investigate the physiologic responses of whole osteoarthritic synovium to cycle tensile strain. We obtained 3 matched synovial tissue samples from 6 patients undergoing total knee arthroplasty, subjected them to cyclic tensile strain, and then performed gene expression profiling analysis using RNA seq from each cyclic tensile strain protocol.

ORGANISM(S): Homo sapiens

PROVIDER: GSE205196 | GEO | 2022/09/30

REPOSITORIES: GEO

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Differential expression analysis of human small RNAs in young normal, old normal (protected)) and old osteoarthritis (unprotected ) knee cartilage

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Tensile strain and altered synovial tissue metabolism in human knee osteoarthritis

Project description:Tensile strain and altered synovial tissue metabolism in human knee osteoarthritis

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Expression data from total knee arthroplasty patients

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