Genomics

Dataset Information

0

Atlas of target genes of thyroid hormone (TH) in mice


ABSTRACT: We gathered in a single database available RNAseq and ChIPseq data to better characterize the target genes of the thyroid hormone receptors in several cell types. This database can serve as a resource to analyze the mode of action of the hormone. Also, it is an easy-handling convenient tool to obtain information on specific genes in regards to T3 regulation, or extract larger list of genes of interest based on the users’ criteria. Overall, this atlas is a unique compilation of recent sequencing data focusing on thyroid hormones, their receptors, mode of action, targets and roles which may profit researchers within the field. A preliminary analysis indicates extensive variations in the repertoire of target genes which transcription is upregulated by chromatin-bound nuclear receptor. Although it has a major influence, chromatin accessibility is not the only parameter that determines the cellular selectivity of hormonal response.

ORGANISM(S): Mus musculus

PROVIDER: GSE210975 | GEO | 2022/08/12

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-08-12 | GSE210976 | GEO
2010-05-16 | E-GEOD-16075 | biostudies-arrayexpress
2012-12-31 | E-GEOD-38539 | biostudies-arrayexpress
2022-04-29 | GSE201124 | GEO
2018-08-21 | GSE110372 | GEO
2006-03-06 | E-GEOD-4345 | biostudies-arrayexpress
2010-05-16 | E-GEOD-16074 | biostudies-arrayexpress
2010-05-16 | E-GEOD-16017 | biostudies-arrayexpress
2010-05-16 | E-GEOD-16018 | biostudies-arrayexpress
2012-12-31 | E-GEOD-38347 | biostudies-arrayexpress