Transcriptional changes induced by ADH5 knocking out in HeLa cells.
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ABSTRACT: ADH5 encodes for the protein GSNOR, an alchol dehydrogenase acting as a denitrosylase. GSNOR reduces S-nitrosoglutathione (GSNO) to an unstable intermediate, S-hydroxylaminoglutathione, which then rearranges to form glutathione sulfonamide, or in the presence of GSH, forms oxidized glutathione (GSSG) and hydroxylamine
ORGANISM(S): Homo sapiens
PROVIDER: GSE211114 | GEO | 2022/12/21
REPOSITORIES: GEO
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