Transcriptomics

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CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs

ABSTRACT: In this study, we demonstrate that we can obtain human iPSC-derived pancreatic islet-like cells (iPICs) with comparable transcriptomic profile by using a combination of an ALK5 inhibitor and a CDK8/19 inhibitor, instead of utilizing ALK5 inhibitor II.

ORGANISM(S): Homo sapiens

PROVIDER: GSE215152 | GEO | 2022/12/08

REPOSITORIES: GEO

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