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Characterization of in vitro cultured alveolar macrophages (AM) transcriptomes

ABSTRACT: To identify molecular characteristics of mouse AMs stimulated with or without Poly(I:C) in the presence of vehicle or MSDC overnight in vitro, we isolated RNA from AMs with various treatments and examined by bulk RNA-seq. We found a large number of cytokine gene profiles were reduced following MSDC treatment in WT AMs, suggesting that MSDC treatment recuced inflammatory response in AMs.

ORGANISM(S): Mus musculus

PROVIDER: GSE216564 | GEO | 2023/12/02

REPOSITORIES: GEO

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