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Gene expression changes in mouse hippocampus after overnight exposure to corticosterone

ABSTRACT: The aim of the experiment was to test the effect of elevated level of corticosterone on hippocampal transcriptome after 12 hours of treatment during active phase to mimic the effect of a day-long stress. Additionally, we also tested the decay time of transcriptomic response during resting period when the level of glucocorticoids returns to the baseline. Our study shows that transcriptomic responses to glucocorticoids are heterogenous in terms of the decay time with some genes displaying persistent changes in expression during 9 hours of rest.

ORGANISM(S): Mus musculus

PROVIDER: GSE218508 | GEO | 2022/11/24

REPOSITORIES: GEO

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