Proteomics

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The effect of corticosterone treatment on the proteome of mouse brain endothelial bEnd.3 cells


ABSTRACT: Elevated glucocorticoids feature body’s responses to a variety of psychological and physiological stressors. To understand how glucocorticoids affect brain endothelial cells that form the blood-brain barrier, we applied quantitative proteomics to study changes in the proteome of a mouse brain endothelial cell line, bEnd3, upon acute 24-hour treatment with 5 uM corticosterone in vitro.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Endothelial Cell

SUBMITTER: Alexei Leliavski  

LAB HEAD: Gurumoorthy Krishnamoorthy

PROVIDER: PXD022166 | Pride | 2021-03-01

REPOSITORIES: Pride

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