Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of PD-1 knockout on Mtb infection

ABSTRACT: To investigate the effect pf PD-1 knockout during Mtb infection, wild type mice and PD-1 knockout mice were infected with Mtb and BMDC were isolated for the transcriptome analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE219261 | GEO | 2023/12/25

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Effect of PD-1 knockout on Mtb infection

Project description:Effect of PD-1 knockout on Mtb infection

| PRJNA907818 | ENA

PD-1 Knockout Engineered T Cells for Advanced Colorectal Cancer with MSI high expression

Project description:Interventions: experimental group :PD-1 Knockout Engineered T Cells Primary outcome(s): Number of participants with Adverse Events and/or Dose Limiting Toxicities as a Measure of Safety and tolerability of dose of PD-1 Knockout T cells using Common Terminology Criteria for Adverse Events (CTCAE v4.0) in patients Study Design: historical control

| 2662961 | ecrin-mdr-crc

Impaired neutrophil recruitment in CXCL5 knockout mice during Mtb infection

Project description:Comparison of Mycobacterium tuberculosis infection in WT mice strain C57BL/6 (WT) and the CXCL5 knockout (KO)

2014-09-02 | GSE43337 | GEO

Impaired neutrophil recruitment in CXCL5 knockout mice during Mtb infection

Project description:Comparison of Mycobacterium tuberculosis infection in WT mice strain C57BL/6 (WTM-BM-^]) and the CXCL5 knockout (KO) Two color arrays with dye swaps, RNA harvested at day 0 (d00, no infection) and day 21 (d21); 5 mice per experimental group. RNA from each experimental group was pooled. The e0, e8, e9 and eX are internal experimental run/labels of equivalent biological replications of the experiments.

2014-09-02 | E-GEOD-43337 | biostudies-arrayexpress

RNA sequencing of mammary glands from 55-day old control, MTB-200ba429, MTB-IGFIR, MTB-IGFIRba429 mice.

Project description:RNA was isolated from mammary glands from 55 day old control mice, mice overexpressing the miR-200b/200a/429 cluster in mammary epithelial cells (MTB-200ba429) mice overexpressing the IGF-IR transgene in mammary epithelial cells (MTB-IGFIR), and mice overexpressing both the miR-200b/200a/429 cluster and the IGF-IR transgene in mammary epithelial cells (MTB-IGFIRba429)

2021-09-17 | GSE180264 | GEO

Impact of Wnt6 knockout in Mtb infected murine BMDM

Project description:Impact of Wnt6 knockout in Mtb infected murine BMDM

| PRJNA671683 | ENA

Global transcriptomic profiles of blood monocytes from Hmox1 homozygous knockout mice compared to wild type controls following Mtb infection

Project description:Since whole blood transcriptome profiling has been proposed as a reliable measure of immune responses in TB patients and because the plasma levels of HO-1 have been suggested as a potential TB diagnostic marker, we wanted to see the differences in the global transcriptomic profiles and the downstream pathways in the blood monocytes isolated from Mtb-infected HO-1 Wt and KO mice.

2019-03-05 | E-MTAB-7221 | biostudies-arrayexpress

CoMtb alters the immune landscape following Mtb infection [B6 scSCRNAseq]

Project description:To characterize the influence of CoMtb on immune responses during infection, we performed single-cell RNA sequencing (scRNAseq) and flow cytometry analysis of lungs from Mtb-infected C57Bl/6 mice with and without CoMtb immediately pre-infection and at 10, 17 and 34 days after conventional dose (50-100 CFU) Mtb infection. We found that CoMtb induces rapid recruitment and activation of T cells, macrophage, and diminished late neutrophil responses.

2024-06-18 | GSE266233 | GEO

THP1 cell response to Mycobacterium tuberculosis infection and Mtb PAMP stimulation

Project description:To compare gene expression changes induced by infection with Mycobacterium tuberculosis (Mtb) with changes induced by purified Mtb products, we infected THP-1 cells with Mtb strain H37Rv or treated with purified Mtb products, then performed RNAseq.

2023-05-15 | GSE227851 | GEO

Aeromonas sp. MTB isolate:MTB

Project description:Aeromonas sp. MTB isolate:MTB Genome sequencing and assembly

| PRJNA1083721 | ENA