Transcriptomic characterization of control and drug-treated APOB-mutant organoids to study steatosis-resolving drug effects
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ABSTRACT: We treated APOB-mutant organoids with different anti-NAFLD drug candidates that were effective at resolving steatosis. To understand the mechanisms of drug action and adverse drug effects we performed bulk RNA-sequencing on drug-treated and vehicle-treated APOB mutant organoids.
ORGANISM(S): Homo sapiens
PROVIDER: GSE221705 | GEO | 2023/02/23
REPOSITORIES: GEO
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