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Effect of hPNPase on Escherichia coli transcritome after addition of rifampicin

ABSTRACT: We replaced the natural pnp locus with the human cDNA and studied the transcriptomes of 3 strains, namely the wt pnp+ (C-1a), the mutant with pnp ORF deletion (C-5691) and the strain with the substitution of the bacterial ORF with the human one (C-6001), before and 4 minutes after the addition of rifampicin to inhibit transcription.

ORGANISM(S): Escherichia coli

PROVIDER: GSE221825 | GEO | 2023/08/08

REPOSITORIES: GEO

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Effect of hPNPase on Escherichia coli transcritome

Project description:We replaced the natural pnp locus with the human cDNA and studied the transcriptomes of 3 strains, namely the wt pnp+ (C-1a), the mutant with pnp ORF deletion (C-5691) and the strain with the substitution of the bacterial ORF with the human one (C-6001).

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Effect of hPNPase on Escherichia coli transcritome after addition of rifampicin

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