Nanostring gene expresson-based, antibody activation of bone marrow derived macrophages (BMDM)
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ABSTRACT: We study immune responses induced by amyloid targeting antibodies and CAA-mediated microhemorrhages using histology and gene expression analyses in AD mouse models and primary culture settings. We cultured and plated primary bone marrow-derived macrophages in wells coated with high Fc receptor activating antibody IgG2a or isotype control antibody harboring the LALAPG mutation, ablating Fc-FcR mediated effector functions
ORGANISM(S): Mus musculus
PROVIDER: GSE222466 | GEO | 2023/09/14
REPOSITORIES: GEO
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