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Responders to immune checkpoint therapy display early clonal expansion of tumour-infiltrating lymphocytes

ABSTRACT: Using murine models that exclude variation in host genetics, environmental factors and tumour mutation burden, limiting variation between animals to naturally diverse TCRβ repertoires, we applied bulk TCRseq to study TCRβ repertoire dynamics in ICT responders and non-responders

ORGANISM(S): Mus musculus

PROVIDER: GSE222575 | GEO | 2024/05/08

REPOSITORIES: GEO

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