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Effect of Bcl11b deletion in resting and activated mouse CD4+ T cells.

ABSTRACT: To investigate the function of Bcl11b in activated C57Bl/6 mouse CD4+ T cells, we deleted Bcl11b in vivo using a Bcl11b-fl/fl;Cd4cre-ert2 tamoxifen-inducible strategy. We then cultured CD4 T cells isolated from these mice 3 days in resting or activating condtions. Finally, we performed gene expression profiling analysis using data obtained from RNA-seq of 3-5 samples per genotype per condition.

ORGANISM(S): Mus musculus

PROVIDER: GSE223334 | GEO | 2023/01/20

REPOSITORIES: GEO

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