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Investigating how the SPT-2 histone chaperone affects chromatin structure in C. elegans.

ABSTRACT: Histone chaperones play essential roles in the regulation of chromatin structure. Here, we investigated how the SPT-2 histone chaperone controls chromatin structure and accessibility in C. elegans. To achieve this, we performed ATAC-seq comparing WT N2 worms to spt-2 KO or spt-2 histone binding mutant (spt-2 M627A) worms.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE224799 | GEO | 2023/02/09

REPOSITORIES: GEO

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