AP-1 signaling modulates cardiac fibroblast stress responses
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ABSTRACT: This study aimed to evaluate the genomic effects of single nucleotide polymorphisms (SNPs) at the 9p21 locus that are clinically correlated with heart disease. We performed ATAC sequencing on iPSC-derived cardiac fibroblasts and found large differences in AP-1 and GATA family motifs between cells containing the SNPs and those lacking them.
ORGANISM(S): Homo sapiens
PROVIDER: GSE225736 | GEO | 2023/12/13
REPOSITORIES: GEO
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