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CD73 sorted cell RNA-sequencing and GeoMX sequencing

ABSTRACT: CD73 marks cells with increased mesenchymal morphologies and phenotypes. To understand the transcriptional differences in CD73+ and - cells, we performed bulk RNA-seq on the CD73 sorted cells. In this study, we investigated if and how transcriptional heterogeneity of EwS cells contributes to heterogeneity of tumor phenotypes in vivo. Digital spatial profiling and human whole transcriptome analysis interrogated transcriptomic heterogeneity in EwS CHLA10 cell line xenografts.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226562 | GEO | 2023/07/10

REPOSITORIES: GEO

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