Transcriptomics

Dataset Information

0

Elucidation of the mechanism of treatment by TGFβ inhibitors for the IC/PBS mouse model using hydrogen peroxide


ABSTRACT: Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic disease for which there is no effective treatment.Transforming Growth Factor-β (TGF-β) is thought to be involved in the pathogenesis of IC/PBS, and previous studies have shown that suggested that administration of TGF-β inhibitors significantly ameliorates IC/PBS in a mouse model.However, the molecular mechanism of the therapeutic effect of TGF-β inhibitors on IC/PBS has not been comprehensively analyzed. In this study, we show that TGF-β inhibitor administration ameliorated dysuria in IC/PBS mouse models using hydrogen peroxide through a variety of mechanisms.

ORGANISM(S): Mus musculus

PROVIDER: GSE226802 | GEO | 2023/09/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-06-06 | PXD031843 | Pride
| ST000382 | MetabolomicsWorkbench
2016-04-15 | ST000381 | MetabolomicsWorkbench
| PRJNA941816 | ENA
| PRJNA480489 | ENA
2009-08-25 | E-GEOD-12355 | biostudies-arrayexpress
2009-08-06 | GSE12355 | GEO
2003-07-14 | GSE347 | GEO
2003-07-14 | GSE346 | GEO
2003-07-14 | GSE345 | GEO