Methylation profiling

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DNA methylation analysis by MeDIP-on-chip in mouse E3.5 blastocysts, E6.5 epiblasts and E9.5 whole embryos.

ABSTRACT: DNA methylation is extensively reprogrammed during early phases of mammalian development yet individual genomic targets of this process are largely unknown. We optimized MeDIP (Methylated DNA Immunoprecipitation) for low numbers of cells and profiled DNA methylation genome-wide during early development of the mouse embryonic lineage in vivo.

ORGANISM(S): Mus musculus

PROVIDER: GSE22831 | GEO | 2010/11/01

SECONDARY ACCESSION(S): PRJNA127883

REPOSITORIES: GEO

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