Transcriptomics

Dataset Information

0

Encephalitis and poor neuronal death-mediated control of herpes simplex virus in human inherited RIPK3 deficiency


ABSTRACT: We hypothesize that human RIPK3 deficiency does not result in impairment of type I IFN mediated antiviral immunity, contrasting with the situation in deficiencies of the TLR3-IFNAR1 circuit. To test the cellular responses to HSV1 at the wide transcriptome level, bulk RNA sequencing was performed with human primary fibroblasts without or with HSV-1 infection for 24 hours, in cells from healthy controls, RIPK3 HSE patient and other patients with recessive TLR3, IFNAR1 or NEMO deficiency.

ORGANISM(S): Homo sapiens

PROVIDER: GSE228495 | GEO | 2023/03/29

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2020-09-24 | GSE157948 | GEO
2022-06-09 | E-MTAB-11540 | biostudies-arrayexpress
2022-10-10 | GSE201450 | GEO
2013-02-04 | E-GEOD-43362 | biostudies-arrayexpress
2022-08-12 | PXD026533 | Pride
2022-09-18 | GSE213606 | GEO
2021-10-29 | GSE168799 | GEO
2011-10-20 | GSE32390 | GEO
2014-04-02 | E-GEOD-51526 | biostudies-arrayexpress
2021-02-08 | GSE165916 | GEO