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Effect of FOSL1 and HDAC2 knockdown on gene expression in cancer cell lines

ABSTRACT: We identifled FOSL1 and HDAC2 as master regulators of cancer cell metabolism. To validate their function, we knockdown FOSL1 in pancreatic adenocarcinoma cell line PANC-1 and HDAC2 in lung adenocarcinoma cell line H1299, respectively. Then RNA-seq was performed to investigate the alterations of metabolic genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE230729 | GEO | 2024/04/27

REPOSITORIES: GEO

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Effect of FOSL1 and HDAC2 knockdown on gene expression in cancer cell lines

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