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Cranioencephalic functional lymphoid units in glioblastoma

ABSTRACT: We used single cell RNA sequencing to profile the immune cell repertoire of tumor tissue, peripheral blood mononuclear cells (PBMC), bone marrow mononuclear cells (BMMC) from distal bone and cranial (skull) bone from human treatment-naive glioblastoma patients. For comparison, we obtained and analyzed control samples (cranial bone and PBMC) from human non-malignant intracranial disease.

ORGANISM(S): Homo sapiens

PROVIDER: GSE233304 | GEO | 2024/06/14

REPOSITORIES: GEO

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