Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Homo sapiens Drosophila melanogaster

PROVIDER: GSE235332 | GEO | 2025/02/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure [human]

Project description:The diagnosis of Parkinsonism is based on motor symptoms that are caused by reduced dopaminergic output However, decades earlier, patients report non-motoric problems, including hyposmia It is not known if non-motor and motor defects are causally connected Here we used single-cell transcriptome sequencing (10x) of young and olf fly mutants (whole brain) and human patients (three regions: nucleus basalis of Meynert, nucleus accumbens and putamen). This atlas reveals early defects in cholinergic neurons that are recapitulaed across species

2025-02-25 | GSE235330 | GEO

Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure [fruit fly]

2025-03-01 | GSE228843 | GEO

Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure

Project description:Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure

| PRJNA985700 | ENA

Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure [human]

Project description:Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure [human]

| PRJNA985706 | ENA

Anti-microRNA-21 prevents kidney failure in Alport syndrome by stimulating metabolic pathways

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-01-01 | E-GEOD-62295 | biostudies-arrayexpress

Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-12-01 | E-GEOD-52251 | biostudies-arrayexpress

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

Project description:This SuperSeries is composed of the SubSeries listed below.

2011-07-26 | GSE29774 | GEO

Anti-microRNA-21 prevents kidney failure in Alport syndrome by stimulating metabolic pathways

Project description:This SuperSeries is composed of the SubSeries listed below.

2015-01-01 | GSE62295 | GEO

Identification of Drug Candidates Rescuing SARS-CoV-2 Infection Induced Dopaminergic Neuron Senescence

Project description:RNA-seq analysis was applied to examine the mock or SARS-CoV-2 infected DA neurons.We found SARS-CoV-2 infection caused DA neurons senescence.We also found several drug candidates block SARS-CoV-2 infection caused senescence of hPSC-derived DA neurons. RNA-seq was applied to analyze the drug candidates or DMSO treated DA neurons upon SARS-CoV-2 infection. The genes involved in senescence pathway were rescued in riluzole, metformin or imatinib treated DA neurons.

2022-10-01 | GSE156761 | GEO

CDK12 prevents MYC-induced transcription-replication conflicts

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-06-19 | GSE236553 | GEO