Genomics

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Sciatic nerve FAIRE-chip and ChIP-Chip with Egr2/Krox20 and Sox10


ABSTRACT: Egr2/Krox20 and Sox10 regulate genes involved in formation of myelination in the peripheral nervous system. ChIP-chip assays were performed on rat sciatic nerve at P15, a peak timepoint of myelination. In addition, Faire was used to identify areas of open chromatin. This experiment includes a custom ChIP-chip design incorporating many genes that are dynamically regulated during peripheral nerve myelination. Two antibodies were used for Egr2, Abcam and Covance PRB-236P.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE23648 | GEO | 2010/10/15

SECONDARY ACCESSION(S): PRJNA130963

REPOSITORIES: GEO

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