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Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in Christianson Syndrome cell model

ABSTRACT: To investigate the function NHE6 protein, we established HAP1 CRISPR-CAS9 SLC9A6 Knockout lines and their paired controls . We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells, each with 6 replicates, at two time points.

ORGANISM(S): Homo sapiens

PROVIDER: GSE246263 | GEO | 2023/10/30

REPOSITORIES: GEO

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Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in Christianson Syndrome cell model

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