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Gene expression analysis of mouse F1 hybrids to study cis regulatory variations

ABSTRACT: To analyze the difference in gene expression between alleles of F1 hybrids of mouse C57BL6/J (B6) and MSM/Ms (MSM) strains, we sequenced these F1 hybrids of reciprocal crosses. While most genes did show allelic bias, a small number of genes showed either B6- or MSM-biaed expression in both crosses. These allelic differences were associated with the allelic differences in histone acetylation in promoter regions determined by another experiments.

ORGANISM(S): Mus musculus

PROVIDER: GSE246401 | GEO | 2024/05/31

REPOSITORIES: GEO

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