Transcriptomics

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Transcriptome analysis of NK92 teated with PPMX-T003 for connectivity scoring analysis


ABSTRACT: PPMX-T003, an humanized anti-transferrin receptor 1 inhibitory antibody, has anti-neoplastic potential against mature NK cell neoplasms. However, its molecular mechanism is not elucidated. To investigate, we performed RNAseq of NK92 cells treated with PPMX-T003 to obtain defferentially expressed gene signature and compared it to those of well-known anti-neoplastic agents for prediction of similarity in transcriptomic change.

ORGANISM(S): Homo sapiens

PROVIDER: GSE246532 | GEO | 2024/06/10

REPOSITORIES: GEO

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