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Single cell transcriptome analysis of primary ANKL cells derived from ANKL-PDX treated with PPMX-T003

ABSTRACT: PPMX-T003, an humanized anti-transferrin receptor 1 inhibitory antibody, has anti-neoplastic potential against ANKL. However, phenotype of refractory subclone of ANKL against PPMX-T003 remains unclear. To investigate, we performed single cell transcriptome analysis of ANKL1, a primary ANKL cells derived from ANKL-patient-derived xenograft mouse model (ANKL-PDX) with/without treatment of PPMX-T003 injection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE246533 | GEO | 2024/06/10

REPOSITORIES: GEO

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