Transcriptomics

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Neonatal beta cells lack the specialized metabolic phenotype of mature beta cells


ABSTRACT: Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. This unresponsiveness may be due to a generalized immaturity of the metabolic pathways normally found in beta cells. Gene expression profile of neonatal (1 day old) and young adult (6 weeks old) Sprague-Dawley rat islets were evaluated and compared.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE24790 | GEO | 2011/02/22

SECONDARY ACCESSION(S): PRJNA132245

REPOSITORIES: GEO

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