Defining the mechanism of systemic NK cell dysfunction associated with melanoma lung metastasis in spontaneous and experimental models
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ABSTRACT: We isolated dysfunctional splenic NK cells in mice with melanoma metastasis and performed bulk RNA-seq with the NK cells to explore the mechanism of NK cell dysfunction with a special focus on signaling pathway linked to NK cell cytotoxicity.
ORGANISM(S): Mus musculus
PROVIDER: GSE248264 | GEO | 2024/08/27
REPOSITORIES: GEO
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