Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomics of PTEN knockout B16-F10 cells in C57BL/6J mice model treated with PTEN

ABSTRACT: extracellular PTEN treatment did not affect the growth of PTEN knockout B16-F10 cells cultured in vitro. , To investigate whether extracellular PTEN act on the tumor microenvironment to exert a tumor-suppressive role in vivo，molecular changes caused by PTEN treatment inside the B16-F10-PTEN tumors were monitored by RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE249142 | GEO | 2024/07/24

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Effect of PTEN treatment on the subcutaneous tumor formation model of PTEN knockout B16F10 cells in C57BL/6J mice

Project description:PTEN treatment can affect the tumor growth of PTEN knockout B16-F10 cells in C57BL/6J mice，We hope to analyze the changes that occur in various cells in tumors through single-cell RNA sequencing.

2024-07-24 | GSE249052 | GEO

B16-F10 RNA-Seq

Project description:RNA-Seq of B16-F10 mouse melanoma cell line and gene expression profiling

2014-01-31 | E-MTAB-2271 | biostudies-arrayexpress

proteome analysis of Lung tissue of mice bearing B16-F10-luc-G5 melanoma tumor with sleep fragmentation and with or with out the asdmistration of GL-pp

Project description:Proteome analysis of Lung tissue of mice bearing B16-F10-luc-G5 melanoma tumor with sleep fragmentation and with or with out the asdmistration of GL-pp. The mice were randomly divided into 4 groups: control group in general condition with no further treatment (CON group), tumor group with the burden of B16-F10-luc-G5 cells (Tumor group), T+SF group with SF and the burden of B16-F10-luc-G5 cells (T+SF group), and GL-pp group with SF, tumor cells burden, and the administration of 80 mg/kg GL-pp (GL-pp group). B16-F10-luc-G5 cells (5 × 1000000 cells/100 µL per mouse) were injected into the mice through the tail vein. The lung tissue of T+SF group and GL-pp group were analyzed by the proteome.

2021-09-10 | PXD025171 | Pride

B16-F10 RNA-Seq

Project description:B16-F10 RNA-Seq

| PRJEB5299 | ENA

RNA-seq of B16-F10 cells cultured on the ECM of SMCs treated with siRNA and B16-F10 tumor conditioned media

Project description:The objective of this study was to profile B16-F10 cells grown in vitro on the extracelllular matrix generated by SMCs treated with siRNA and conditioned media

2017-09-19 | GSE96972 | GEO

Effect of depletion of HOIP on gene expression during B16-F10 melanoma tumor development in immunedeficinet mice.

Project description:To investigate the cooperative function LUBAC E3 ligase complex during tumor development, we established HOIP-knockout B16-F10 murine melanoma cell lines.

2024-04-01 | GSE206472 | GEO

NanoString Analysis of Gene Expression in B16.F10 Tumors Treated with the cGAS Activator, NanoISD

Project description:Characterization of the immune profile (i.e. tumor RNA) of a murine B16.F10 tumor 6 hours post a single 100 µL intratumoral injection of 2 µg NanoISD, Free D-PDB at an equivalent dose, or PBS.

2021-09-01 | GSE183144 | GEO

Transcriptome analysis of Control and FBXO38 knockdown B16-F10 tumor issue

Project description:F-box only protein 38 (FBXO38), which belongs to SKP1-CUL1-F-box protein (SCF) family, exhibits the ability to mediate Lys48-linked poly-ubiquitination and subsequent proteasome degradations of PD-1.To investigate the effect of FBXO38 knockdown on transcription in tumor, we performed RNA-seq in control and FBXO38 knockdown B16-F10 tumor issue.

2024-02-07 | GSE246258 | GEO

RNA-seq profiling of cultured B16 F0, F1 and F10 cells

Project description:To contrast and compare the transcriptomes of poorly metastatic B16 sub-clones F0 and F1 to the highly metastatic sub-clone F10.

2021-08-31 | GSE182970 | GEO

Mouse melanoma cell line B16-F10 treated with G007-LK

Project description:The mouse melanoma cell line B16-F10 provided by American Type Culture Collection (ATCC® CRL-6475™) were treated with DMSO, G007-LK, WNT or G007-LK+WNT, done in triplicates for a total of 12 samples.

2021-07-01 | E-MTAB-8101 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data