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Single cell RNA sequencing of mouse blood during acute pancreatitis and recovery

ABSTRACT: Acute pancreatitis (AP) is an inflammatory disease with a mild to severe course, local and systemic complications, and a high mortality rate. Macrophage activation correlates with disease severity.Single cell RNA-sequencing was performed to identify inflammatory signals during AP and recovery using the blood from experimental AP model. We demonstrate that myeloid-ANXA1 expression is upregulated in peripheral blood during the initial phase of AP.

ORGANISM(S): Mus musculus

PROVIDER: GSE249349 | GEO | 2023/12/10

REPOSITORIES: GEO

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