Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The expression data from mandibular arch and tongue primordia in mouse embryos.

ABSTRACT: The mouse hypoglossal nerve originates from the occipital motor nuclei and projects a long distance, reaching the vicinity of the tongue primordia, the lateral lingual swelling, at E11.5. However, the details of how the hypoglossal nerve correctly projects to the primordia are not well understood. To investigate the molecular basis of hypoglossal nerve elongation, we employed cDNA microarray technology and screened for candidate genes involved in the axon guidance event.

ORGANISM(S): Mus musculus

PROVIDER: GSE249490 | GEO | 2023/12/06

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

The expression data from mandibular arch and tongue primordia in mouse embryos.

Project description:The expression data from mandibular arch and tongue primordia in mouse embryos.

| PRJNA1049379 | ENA

MicroRNA expression signatures for developing tongue primordia in mouse embryos

Project description:We aimed to understand the molecular basis of muscular development in tongue. We focused on the critical stages of tongue myogenesis, namely, E10.5 (settlement of myogenic progenitors in tongue primordium), E11.5 (initiation of myoblast differentiation with the development of lateral lingual swellings). We conducted miRNA microarray analysis of the tongue primordia at E10.5 and E11.5, during which myoblast differentiation was induced as a result of the activation of muscle regulatory gene expression. The medial part of the fused mandibular prominences that corresponds to a tongue primordium were collected from E10.5 and E11.5 mouse embryos. Forty embryos for each time-point were used to obtain a pool of total RNA.

2014-03-11 | E-GEOD-51364 | biostudies-arrayexpress

MicroRNA expression signatures for developing tongue primordia in mouse embryos

2014-03-11 | GSE51364 | GEO

Gene expression change in the lingual nerve and the traumatic neuromas after the injured lingual nerve.

Project description:The lingual nerves are incidentally injured in many oral and maxillofacial surgical procedures, traumatic neuroma was observed at the proximal stump of the injured lingual nerve in patients with severe lingual nerve disturbance. Various genes including genes related to nerve regeneration are expressed in the rat and mouse traumatic neuroma, as regeneration mechanism works after lingual nerve injury. Few reported have showed the expressed genes in the traumatic neuroma of the human lingual nerve. In this study, we compared the gene expression between pooled RNA sample from three traumatic neuromas removed in microneurosurgery in the lingual nerve and an RNA sample from the normal lingual nerve on the unaffected side of the removed tongue with cancer. The 2,357 genes increased more than twofold in the traumatic neuroma compared with the normal lingual nerve. Then, we analyzed the upregulated genes in DAVID and DAVID indicated that the 20 upregulated genes were associated with protein secretion to the extracellular space in the pathways. This study identified the 20 candidate genes at the nerve regeneration stage in the traumatic neuroma in the human lingual nerve.

2022-01-04 | GSE124668 | GEO

mRNA sequencing of epithelial cells from the esophagus and tongue

Project description:In this study, we used RNA sequencing to characterize a new population of taste buds found in the esophagus and compared them to their lingual counterpart. We concluded that esophageal taste buds share many markers with lingual taste buds althoug they seem to express less taste receptors in average.

2023-03-09 | GSE220064 | GEO

slmp mutant in tomato leaf primordia

Project description:slmp mutant in tomato leaf primordia

| PRJNA530516 | ENA

Gene expression change in the lingual nerve and the traumatic neuromas after the injured lingual nerve.

Project description:Gene expression change in the lingual nerve and the traumatic neuromas after the injured lingual nerve.

| PRJNA513034 | ENA

Gill developmental program in the teleost mandibular arch.

Project description:Whereas no known living vertebrate possesses gills derived from the jaw-forming mandibular arch, it has been proposed that the jaw arose through modifications of an ancestral mandibular gill. Here, we show that the zebrafish pseudobranch, which regulates blood pressure in the eye, develops from mandibular arch mesenchyme and first pouch epithelia and shares gene expression, enhancer utilization, and developmental gata3 dependence with the gills. Combined with work in chondrichthyans, our findings in a teleost fish point to the presence of a mandibular pseudobranch with serial homology to gills in the last common ancestor of jawed vertebrates, consistent with a gill origin of vertebrate jaws.

| S-EPMC9239679 | biostudies-literature

Genome-Wide High Resolution Expression Pattern of Crown Root Primordia in Rice

Project description:RNA sequencing data from laser microdissected crown root primordia (CRP) during CRP initiation (stage-I) and CRP outgrowth (stage-II) as compared to competent tissues (control)

2022-04-24 | GSE185198 | GEO

Tongue and lateral upper airway movement with mandibular advancement.

Project description:STUDY OBJECTIVES: To characterize tongue and lateral upper airway movement and to image tongue deformation during mandibular advancement. DESIGN: Dynamic imaging study of a wide range of apnea hypopnea index (AHI), body mass index (BMI) subjects. SETTING: Not-for-profit research institute. PARTICIPANTS: 30 subjects (aged 31-69 y, AHI 0-75 events/h, BMI 17-39 kg/m(2)). INTERVENTIONS: Subjects were imaged using dynamic tagged magnetic resonance imaging during mandibular advancement. Tissue displacements were quantified with the harmonic phase technique. MEASUREMENTS AND RESULTS: Mean mandibular advancement was 5.6 ± 1.8 mm (mean ± standard deviation). This produced movement through a connection from the ramus of the mandible to the pharyngeal lateral walls in all subjects. In the sagittal plane, 3 patterns of posterior tongue deformation were seen with mandibular advancement-(A) en bloc anterior movement, (B) anterior movement of the oropharyngeal region, and (C) minimal anterior movement. Subjects with lower AHI were more likely to have en bloc movement (P = 0.04) than minimal movement. Antero-posterior elongation of the tongue increased with AHI (R = 0.461, P = 0.01). Mean anterior displacements of the posterior nasopharyngeal and oropharyngeal regions of the tongue were 20% ± 13% and 31% ± 17% of mandibular advancement. The posterior tongue compressed 1.1 ± 2.2 mm supero-inferiorly. CONCLUSIONS: Mandibular advancement has two mechanisms of action which increase airway size. In subjects with low AHI, the entire tongue moves forward. Mandibular advancement also produces lateral airway expansion via a direct connection between the lateral walls and the ramus of the mandible. CITATION: Brown EC; Cheng S; McKenzie DK; Butler JE; Gandevia SC; Bilston LE. Tongue and lateral upper airway movement with mandibular advancement. SLEEP 2013;36(3):397-404.

| S-EPMC3571744 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data