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Comparison of the expression profiles of 630E strain after 4h and 10h of growth

ABSTRACT: Transcriptional profiling of C. difficile 630E strain after 4h vs 10h of growth

ORGANISM(S): Clostridioides difficile

PROVIDER: GSE25474 | GEO | 2011/08/22

SECONDARY ACCESSION(S): PRJNA142595

REPOSITORIES: GEO

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Comparison of the expression profiles of 630E strain after 4h and 10h of growth

Project description:Transcriptional profiling of C. difficile 630E strain after 4h vs 10h of growth Two-conditions experiments, 630E strain 4h vs 630E strain 10h, 4 biological replicates for each condition

2011-08-21 | E-GEOD-25474 | biostudies-arrayexpress

Comparison of the expression profiles of 630E strain and a sigH mutant after 10h of growth

Project description:Transcriptionnal profiling of C. difficile 630E strain vs a sigH mutant after 10h of growth in TY

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Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY.

Project description:Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY

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Comparison of the expression profiles of 630E strain and a sigH mutant after 10h of growth

Project description:Transcriptionnal profiling of C. difficile 630E strain vs a sigH mutant after 10h of growth in TY Two-conditions experiments, 630E strain 10h vs sigH mutant 10h, 4 biological replicates for each condition

2011-08-21 | E-GEOD-25475 | biostudies-arrayexpress

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY with 0.5% glucose.

Project description:Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY with 0.5% glucose

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Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY.

Project description:Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY two-conditions experiments, WT strain vs ccpA mutant strain, 4 biological replicates for each condition, in an indirect design using a 8h TY RNA preparation as Reference

2012-10-02 | E-GEOD-35071 | biostudies-arrayexpress

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY with 0.5% glucose.

Project description:Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY with 0.5% glucose two-conditions experiments, WT strain vs ccpA mutant strain, 4 biological replicates for each condition, in an indirect design using a 8h TY RNA preparation as Reference

2012-10-02 | E-GEOD-35070 | biostudies-arrayexpress

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant

Project description:This SuperSeries is composed of the following subset Series: GSE35070: Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY with 0.5% glucose. GSE35071: Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY. GSE35072: Clostridium difficile CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY GSE35073: Clostridium difficile mutant ccpA CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY Refer to individual Series

2012-10-02 | E-GEOD-35152 | biostudies-arrayexpress

Comparison of the expression profiles of the 630E (JIR8094) strain and a prdR mutant (LB-CD8) after 4h growth in TY supplemented with L-proline

Project description:Clostridium difficile, a proteolytic Gram-positive anaerobe, has emerged as a significant nosocomial pathogen. Stickland fermentation reactions are thought to be important for growth of C. difficile. In Stickland reactions, pairs of amino acids donate and accept electrons, generating ATP and reducing power in the process. Reduction of the electron acceptors proline and glycine requires the D-proline reductase (PR) and the glycine reductase (GR) enzyme complexes, respectively. PrdR, a sigma54-dependent regulator, activates transcription of the PR-encoding genes in the presence of proline and negatively regulates the GR-encoding genes, suggesting that PrdR is a central metabolism regulator that controls preferential utilization of proline and glycine to produce energy via the Stickland reactions. Here, transcriptional profiling of the C. difficile 630E strain vs. a prdR mutant (LB-CD8) after 4h of growth in the presence of proline is performed.

2015-10-01 | GSE42471 | GEO

Comparison of the expression profiles of 630E strain and a sig54 mutant after 6h of growth

Project description:Transcriptional profiling of C. difficile 630E strain vs. a sig54 mutant after 6h of growth in TY.

2020-08-28 | GSE149245 | GEO