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Genomic profiles vary with race and subtype in young African American and European American breast cancer (aCGH)

ABSTRACT: In the United States, African-American (AA) women are more likely to develop early-onset breast cancer and have historically poorer outcomes due to this disease compared to European-American (EA) women. Here, we analyzed genomic profiles of breast tumors from young women (<50 years old), matched by tumor subtype, histological grade, and ethnicity (African-American, AA, compared to European-American, EA). DNA copy number alterations (CNAs) were analyzed using a 32K BAC tiling path array. The study provides insight into the genetic component of ethnicity-related breast cancer health disparities.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26214 | GEO | 2013/01/29

SECONDARY ACCESSION(S): PRJNA142329

REPOSITORIES: GEO

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Genomic profiles vary with race and subtype in young African American and European American breast cancer (SNP)

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Genomic profiles vary with race and subtype in young African American and European American breast cancer (SNP)

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