A Brucella ovis HWE histidine kinase is important for detergent resistance.
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ABSTRACT: Through a system-level analysis of non-essential two-component signal transduction systems (TCS) genes in Brucella ovis, we have discovered that deletion of an HWE histidine kinase, BOV_1602, leads to significant increase in resistance to SDS detergent and other anionic or zwitterionic detergents. To better understand this detergent resistance phenotype, we performed RNA-seq experiment using both WT and ∆BOV_1602 cultured on no stress (TASB) or TSAB supplemented with 0.004% SDS.
ORGANISM(S): Brucella ovis
PROVIDER: GSE262183 | GEO | 2024/03/26
REPOSITORIES: GEO
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