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The effects on the deficient of GDH1 on gene expression in LN229 cells.

ABSTRACT: Glutamine is an important nutriment for cancer cell growth that provides biological sources for nucleic acid and fatty acid synthesis, but the role of glutaminolysis in signal transduction and glioblastoma (GBM) progression remains little known. Here, we investigated whether GDH1, a key glutamate dehydrogenase, affects the expression levels of signal transduction factors by mRNA expression profiling of wild-type and GDH1 knockdown cells of the glioblastoma cell line LN229 cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE268158 | GEO | 2024/06/30

REPOSITORIES: GEO

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