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Gene expression profile at single nuclei resolution of aortas from Ldlr-/- mice with or without defective hepatic glutaminolysis

ABSTRACT: Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is a hallmark of atherosclerotic diseases. We used single nuclei RNA sequencing (snRNA-seq) to analyze the impact of defective hepatic glutaminolysis on cell diversity in atherosclerotic aorta.

ORGANISM(S): Mus musculus

PROVIDER: GSE269682 | GEO | 2024/10/17

REPOSITORIES: GEO

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GLS2 links glutamine metabolism and atherosclerosis by remodelling artery walls (aorta).

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Gene expression profile at single nuclei resolution of aortas from Ldlr-/- mice with or without defective hepatic glutaminolysis

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