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P26 condensates from Pea enation mosaic virus 2 sequester ribosomal components and suppress translation

ABSTRACT: The p26 movement protein of Pea enation mosaic virus 2 (PEMV2) interacts with the 2'-O-methyltransferase fibrillarin within nuclear and cytoplasmic condensates. This study analyzed global 2'-O-methylation patterns in PEMV2-infected Nicotiana benthamiana using RiboMethSeq, focusing on ribosomal RNAs (rRNAs). The aim was to assess whether PEMV2 disrupts rRNA 2'-O-methylation to interfere with host translation or ribosome assembly.

ORGANISM(S): Nicotiana benthamiana

PROVIDER: GSE275487 | GEO | 2024/11/18

REPOSITORIES: GEO

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p26 condensates from Pea enation mosaic virus 2 sequester ribosomal components and suppress translation

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