The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice II

ABSTRACT: To compare gene expression between old C57BL6 female mice treated with either control lentivirus or CRISPRa+ lentivirus, we used a flurorescence-based cell sorting to collect neurons expressing GFP (from the sgRNA) from the hippocampus of the mice from each group.Then we performed gene expression analysis using data obtained from RNA-seq of the old neurons in the hippocampus of both groups.

ORGANISM(S): Mus musculus

PROVIDER: GSE280893 | GEO | 2024/11/06

REPOSITORIES: GEO