Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene Expression Profiling of the hPheo1 Cell Line

ABSTRACT: We investigated the transcriptomic data generated from the hPheo1 cell line We utilized microarrays to pinpoint distinct categories of genes that are either up-regulated or down-regulated, and to clarify the regulatory pathways in hPheo1 cell line.

ORGANISM(S): Homo sapiens

PROVIDER: GSE287491 | GEO | 2025/01/21

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data from breast cancer cell line 4T1

Project description:MiR-9 plays an irreplaceable role in regulating the progression of breast cancer. In order to study the role of miR-9 in promoting MDSC recruitment in the tumor microenvironment, we need to explore the genetic process of miR-9 regulation. We used microarrays to detail the global program of miR-9 down-regulated gene expression and identified different categories of regulated genes in this process.

2024-04-20 | GSE230122 | GEO

CRISPR/Cas9 knock down line

Project description:CRISPR/Cas9 knock down line

| PRJNA521684 | ENA

MicroRNAome of highly metastatic and non-metastatic human breast cell lines

Project description:MicroRNAs are noncoding, endogenous small RNAs that regulate target genes by cleavage of the targeted mRNA or translational repression. We investigated the microRNAome using 2-color microarrays in a highly invasive human breast cancer cell line, MDA-MB-231 (sub line 4175) and a non-invasive breast epithelial cell line, MCF10A. We found 13 miRNAs that were up-regulated and 9 were down-regulated significantly in 4175 cells (p <0.05, fold change >2) compared with MCF10A cells.

2009-07-28 | GSE17350 | GEO

Expression data obtained from HPBALL cell line

Project description:The experiment was designed in order to knock down the expression of TLX3 gene in T-ALL cell line We used microarrays to identify the gene expression signatures associated with TLX3 knock down in HPBALL

2011-11-08 | GSE33540 | GEO

Expression data obtained from ALLSIL cell line

Project description:The experiment was designed in order to knock down the expression of TLX1 gene in T-ALL cell line We used microarrays to identify the gene expression signatures associated with TLX1 knock down in ALLSIL

2011-11-08 | GSE33539 | GEO

Expression data of mouse embryo brain

Project description:Wheather hematopoietic cells contribute to angiogenesis in developing brain, we utilized macrophage deficient mouse embryo. We used microarrays to detect down-regulated genes in KO embryo brain.

2013-05-10 | GSE46800 | GEO

Expression data from mouse basal cell carcinoma (BCC) and normal epidermis, and BCC cell line treated with cyclopamine

Project description:Activation of the Sonic hedgehog (Shh) signaling pathway due to Patched 1 (PTCH1) mutation is a key event in sporadic and familial basal cell carcinoma (BCC) development. To find out the specific pathway for therapeutic intervention, we developed a mouse BCC model by skin specific Ptch1 inactivation, and sought to identify novel Shh targets. We used microarrays to identify up-regulated genes in mouse BCC. We used microarrays to identify down-regulated genes in mouse BCC cell line by cyclopamine.

2018-01-15 | GSE20065 | GEO

RHOQ knock-down Expression data from colorectal cancer cell line HCT-116

Project description:We used microarrays to detail the global gene expression in cell line with or without RHOQ knock-down.

2017-11-13 | GSE106808 | GEO

AR-V7 Targets in Castration-Resistant Prostate Cancer (CRPC) Cell Line

Project description:In order to define the genes responsible for the growth and survival of a human castration-resistant prostate cancer cell line, a short term (doxycycline inducible) knockdown system was developed and utilized. Three independent 22Rv1 cell isolates were derived for each of the following doxycycline-inducible shRNAs (shGFP, shAR3, and shVav3) (AR3 = AR-V7). The cells were grown in androgen depleted conditions, plus or minus doxycycline, for three days. RNA from the 18 samples was then sent to the University of Miami Genetics Core for RNA Integrity Number (RIN) evaluation and microarray analysis. Genes differentially regulated by AR-V7 knock-down or VAV3 knock-down were explored as downstream targets of AR-V7 or VAV3, respectively.

2018-08-16 | GSE104572 | GEO

Gene expression profiling of CD4+ T cell line due to presence of Nef during HIV-1 infection.

Project description:We have utilized microarray technology to compare gene expression profile in presence or absence of Nef during HIV-1 infection in T cell-line. We found several genes significantly differentially regulated due to ∆nef HIV-1 infection and WT HIV-1 infection when compared to Uninfected cells and also several genes significantly dergulated due to WT HIV-1 infection as compared to ∆nef HIV-1 infection. We redistributed genes belonging to several gene ontology into broad categories like “signaling”, “apoptosis”, “transcription” and “lipid metabolism”. We selected some lipid metabolism genes to validate the Nef directed differential expression using quantitative real-time RT-PCR. Thus the present work highlights the importance of Nef directed differential gene expression in milieu of other viral proteins present during infection.

2016-12-06 | GSE76793 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data