Transcriptomics

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Technical and biological variance structure in mRNA-Seq data


ABSTRACT: mRNA expression data from next generation sequencing platforms is obtained in the form of counts per gene or exon. Counts are generally assumed to follow a Poisson distribution in which the variance is equal to the mean. However, it is common in observed count data with biological variation for over-dispersion to be present, i.e., for the variance to be greater than the mean.

ORGANISM(S): Homo sapiens

PROVIDER: GSE29022 | GEO | 2012/07/17

SECONDARY ACCESSION(S): PRJNA140475

REPOSITORIES: GEO

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