To understand which glycan-related genes are involved in the recognition, signaling, and binding of nutrients (HMOs)
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ABSTRACT: Dr. Lebrilla's lab is working on another set of transcriptomics experiments which will measure whether HMO (human milk oligosacharides) elicit a differential response on Caco2 in the presence of B.infantis. They wish to supplement the data obtained with the Illumina platform with glycan-related expression data obtained with the Gene-chips to achieve a more complete understanding on how Caco2 cells respond to the presence of HMOs and B.infantis. The transcriptomics data is being complemented by qPCR based bacterial-epithelial cells binding assays, and glycan arrays assays for which they have initiated a collaboration with the CFG Core H (David Smith).
ORGANISM(S): Homo sapiens
PROVIDER: GSE29934 | GEO | 2011/06/14
SECONDARY ACCESSION(S): PRJNA140881
REPOSITORIES: GEO
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