Transcriptomics

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2.45 GHz Radiofrequency fields alter gene expression in cultured human cells


ABSTRACT: The biological effect of radiofrequency (RF) fields remains controversial. We address this issue by examining whether RF fields can cause changes in gene expression. We observed that 221 genes altered their expression after a 2-hour exposure. The number of affected genes increased to 759 after a 6-hour exposure. Functional classification of the affected genes reveals that apoptosis-related genes were among the up-regulated ones and the cell cycle genes among the down-regulated ones. We observed no significant increase in the expression of heat shock genes. These results indicate that the RF fields at 2.45 GHz can alter gene expression in cultured human cells through non-thermal mechanism. Keywords: gene expression SAGE

ORGANISM(S): Homo sapiens

PROVIDER: GSE3025 | GEO | 2005/07/30

SECONDARY ACCESSION(S): PRJNA93213

REPOSITORIES: GEO

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