Genomics

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Characterization of the small RNAome in acute myeloid leukemia and discovery of novel small RNA species by deep sequencing (Illumina)


ABSTRACT: We used small RNA seq (Illumina) to characterise and quantify the miRNA and small non-coding (snc)RNA transcriptome of 38 libraries of size-fractionated RNA obtained from AML patients and normal bone marrow. We detected the expression of 765 known miRNAs and 2554 uniquely located species of sncRNAs. A total of 575 potential miRNA candidate hairpins were identified. We also identified 37 C/D Box and 51 H/ACA Box, potential novel snoRNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE31335 | GEO | 2017/09/13

SECONDARY ACCESSION(S): PRJNA145991

REPOSITORIES: GEO

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